A 50-year-old Hispanic female presents to your clinic with complaints of
excessive thirst, fluid intake, and urination. She denies any urinary tract infec-
tion symptoms. She reports no medical problems, but has not seen a doctor in
many years. On examination she is an obese female in no acute distress. Her
physical exam is otherwise normal. The urinalysis revealed large glucose, and
a serum random blood sugar level was 320 mg/dL.
What is the most likely diagnosis?
What other organ systems can be involved with the disease?
What is the biochemical basis of this disease?