486
INDEX
Somatostatin, 173, 425
Somatotropin (growth hormone),
424-428
Somogyi effect, 233-240, 236/
Sore throat
in HIV infection, 46
in influenza, 18
Southern blot, 77, 79
Sphincter of Oddi dysfunction, 172
Sphinganine, 255, 256
/
Sphingolipid, 255
Sphingomyelin, 255, 257/
Sphingomyelinase,
259t
Sphingosine, 255
Spina bifida, 36
Splenomegaly, in hemolytic anemia,
209-210
Spliceosome, 47
Squalene, 313, 314/
Stachyose, 231
Starch, 228, 228/
Starvation, 327-337, 330-334/
in anorexia nervosa, 355-356
negative protein balance in, 357-361
Statins (HMG-CoA reductase
inhibitors), 277, 311-317
Stavudine, 50
Steroid hormones, 68, 313, 314/
Steroid-like hormones, 68
Steroid messenger regulation of
translation, 66-73
Stop codons, 86
Streptomycin, 88
Stress
Addison disease and, 435-436
cortisol release and, 445, 447/
herpes simplex virus and, 56
irritable bowel syndrome and,
225-226
Succinate, 133, 135
Succinate dehydrogenase, 133,
134/,
135
Succinate thiokinase,
134/,
135
Succinyl CoA, 133, 388, 388/
Sucrase-isomaltase complex, 219
Sucrose, 219
Sulfatase, 265
Sulfated acetaminophen, 368-369, 369/
Sun exposure, porphyrias and, 405
Supercoiling, 95-96, 96/
Sweat, in cystic fibrosis, 78
T
Tachycardia
in hyperthyroidism, 66
in megaloblastic anemia, 384
in porphyria, 399-400
Tachypnea, in malignant hyperthermia,
164
Taq DNA polymerase, 57-58
Tat protein, 50
Tay-Sachs disease, 253-261,
258/,
259t
TCA cycle.
See
Tricarboxylic acid
(TCA) cycle
Telophase, 29
Template, 48
Termination, in protein synthesis, 86
Tertiary protein structure, 11-12
Tetracyclines
for Lyme disease, 84
mechanisms of action, 88
Tetrahydrobiopterin, 348, 350, 350/
Tetrahydrofolate (THF), 27.
See also
Folic acid
1-carbon carriers of, 29, 38-39,
39/ 40/
in methylation metabolism, 37-38
in purine synthesis, 26, 31
structure, 37, 38/
Thalassemia, 111-118
Thermus aquaticus,
57, 58
Thiaminase enzymes, 144
Thiamine (vitamin B1)
characteristics, 141, 141/
deficiency, 139-140, 143-144
Thiamine pyrophosphate, 141-144,
141/
Thin skin, in hyperthyroidism, 66
Thiocyanate, 148, 153
Thionamide antithyroid drugs, 71-72
Threonine, 376, 378
t
Thrombocytopenia, methotrexate and,
25-26, 31
Thrombolysis, 249
Thromboxane, 294-295
Thromboxane synthase, 296
Thymidylate, 30
Thymidylate synthase, 30,
30/,
387
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