INDEX
473
7-Dehydrocholesterol, 313, 315/
Dehydrogenase (definition), 141
Dehydrogenate complex, 142
3-Dehydrosphinganine, 255, 256/
Delavirdine, 50
Deletion, 123, 125, 126
Dementia, thiamine deficiency
and, 140
Denaturation, 57, 58, 59/
Deoxycholic acid,
286/,
288-289, 306/
Deoxyribose, 27
1
Deoxyribose nucleic acid.
See
DNA
Deoxythymidine 5’-monophosphate
(dTMP), 37
Deoxythymidylate (dTMP), 27,
30/,
31
Deoxyuridine 5-monophosphate
(dUMP), 37
Dermatan sulfate,
266t
Desmopressin acetate, 418
Developmental delay, in phenylke-
tonuria, 348
Dexamethasone suppression test,
444, 445
DHF (dihydrofolate), 30,
30/,
38
DHFR (dihydrofolate reductase), 26,
27, 30, 37, 38
Diabetes insipidus, 417-422
Diabetes mellitus, 197-207, 200-204
/
in Cushing syndrome, 444
glucose homeostasis mechanisms
in, 238
hypoglycemia in, 233-234
Diacylglycerol (DAG), 70, 420, 455
Diaphoresis, in cyanide poisoning,
147-148
Diarrhea
in irritable bowel syndrome,
225-226
in megaloblastic anemia, 384
Didanosine, 50
Dideoxyribonucleotide triphosphates
(ddNTPs), 79
Dietary fiber, 226-231, 227/
Diglyceride, 329
Dihydroceramide, 256
/
Dihydrofolate (DHF), 30,
30/,
38
Dihydrofolate reductase (DHFR), 26,
27, 30, 37, 38
Dihydrolipoyl dehydrogenase, 142
Dihydrolipoyl transacetylase, 142
Dihydropteridine reductase, 348, 350
Dihydroxyacetone phosphate, 246,
246/,
250/
1,25-Dihydroxycholecalciferol,
313,
315/,
457
Dihydroxyphenylalanine (DOPA), 351,
351/
Diiodotyrosine, 412/
Disaccharides, 218, 219
Disease, approach to, 3
Disseminated intravascular
coagulation, 181
Disulfide bonds, in protein structure,
12
Dizziness, in hemolytic anemia, 210
DNA (deoxyribose nucleic acid), 27
folate and, 37-38
methylation, 38, 123, 126
mutations, 105-107
polymerase, 20
recombinant technology, 80-81
replication, 19-20, 46, 47, 105
sequencing methods, 79-80
structure, 19-20
synthesis, 31
transcription, 47-48, 47
/,
85
DNA gyrase, 94, 96, 97
DNA polymerase, 48-49, 105
herpes simplex virus, 57
Taq, 57
DNase, 173
Dopamine, 360
Dopaquinone, 351, 351/
Double helix, 19
Double-strand breaks (DSBs),
106, 107
Drug metabolism, 367
Drug toxicity, 367
Dry skin
in anorexia nervosa, 356
in hypothyroidism, 409-410
Dwarfism, 269, 426
Dyslipidemia, in diabetes, 205
Dyspnea, hyperlipidemia and, 274
E
Ecchymosis, 445
Ectopic ACTH syndrome, 445
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