468
INDEX
Adenine, 19,
271
Adenine phosphoribosyltransferase
(APRT), 393
Adeno-associated virus, for gene
transfer, 80-81
Adenoma, 444
parathyroid, 454
pituitary, 449
Adenopathy, in HIV infection, 46
Adenosine, 40, 393, 394/
Adenosine deaminase, 80, 395
Adenosine diphosphate.
See
ADP
Adenosine monophosphate.
See
AMP
Adenosine 5’-phosphosulfate, 369
Adenosine triphosphate.
See
ATP
Adenosine triphosphate-sulfurylase,
369, 369/
Adenosine triphosphate synthase,
149-152, 150/ 166, 192, 369
Adenovirus, for gene transfer, 80
Adenylate cyclase, 180
activation of, 70,
70t
blood glucose and, 182
cortisol release and, 438, 438/
in ovarian cycle, 431
thyroid hormones and, 411
ADH (antidiuretic hormone),
418-419
Adipose tissue
in fed state, 329, 330/
in postfeeding fast, 331/
in starvation, 334, 334/
ADP (adenosine diphosphate)
in amino acid catabolism, 342
in ATP formation, 150-151, 150/
in carbon monoxide poisoning, 160
in malignant hyperthermia, 166
oxidative phosphorylation and, 135
in rhabdomyolysis, 190, 192
ADP/ATP translocase, 150/
151-152, 152t
Adrenal hyperplasia, 443-449
Adrenal insufficiency, 435-441
Adrenocorticoid deficiency, 435-436
Adrenocorticotropic hormone (ACTH),
436-439,
438/,
444, 447, 447/
Aerobic glycolysis, 245
Aerobic metabolism, 133-135, 134/
Agarose gel, 78
Agitation, in cyanide poisoning,
147-148
Alanine, 342, 378t
Albinism, 351
Albumin, thyroid hormones and, 71
Alcohol consumption
folic acid deficiency and, 35-43
pancreatitis and, 172
porphyrias and, 405
thiamine deficiency and, 139-140,
143-144
Aldolase A, 220
Aldolase B, 220-221, 220/
Aldolase B deficiency, 217-224
Aldolase C, 220
Aldosterone, 418, 420, 439
Allopurinol, 392,
394/,
395
Allosteric effectors, 11
Alloxanthine, 395
a-amylase, 172-174, 219
a 1-antitrypsin deficiency, 340
a-galactosidase A, 259
t
a globin chains, 12
a-helices, 12
a-ketoglutarate, 133,
134/,
249, 341
a-ketoglutarate dehydrogenase (a-
KDGH), 133,
134/,
142, 142/
a-limit dextrin, 174
a-subunit, G protein, 69, 69/
a-thalassemia, 114
Amenorrhea, in anorexia nervosa, 356
Amino acid-derived hormones, 68
Amino acid side chains, 12, 19
Amino acids
branched-chain, 388
catabolism, 341-344,
342/,
358-359, 359/
in cellular signaling, 361
dietary sources, 378-379
essential, 376-381, 378
t
in metabolic process, 357-358, 358/
negative protein balance and,
357-361
nonessential, 376, 377, 378
t
nucleotide codon, 48
utilization, 360-361, 377-378
vegetarian diet and, 375-381
Aminoacyl tRNA, 48
Aminoglycosides, 88, 124
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