CASE 34
A 49-year-old female presents to your clinic for follow-up after initiating a
new medication (lovastatin) for her elevated cholesterol. She is currently with-
out complaints and is feeling well. On repeat serum cholesterol screening,
there is noted to be a decrease in the cholesterol level. The patient asks if she
needs to continue the medication and what the potential side effects and ben-
efits might be. Her physician explains that this medication inhibits the rate-
limiting step and key enzyme in cholesterol biosynthesis.
What is the mechanism of action of this medication?
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