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CASE FILES: BIOCHEMISTRY
B IO C H E M IS T R Y PE A R L S
The major disaccharides obtained in the diet are maltose, sucrose,
and lactose.
Sucrose, or table sugar, is hydrolyzed to glucose and fructose.
Lactose, or milk sugar, is enzymatically converted to glucose and
galactose by P-glycosidase, also located on the brush-border
membrane of the small intestine.
A deficiency in aldolase B leads to the condition known as fructose
intolerance.
REFERENCES
Gitzelmann R, Steinmann B, Van den Berghe G. Disorders of fructose metabolism.
In: Scriver CR, Beaudet AL, Sly WS, et al., eds. The Metabolic and Molecular
Bases of Inherited Disease, 7th ed. New York: McGraw-Hill, 1995.
Semenza G, Auricchio S. Small-intestinal disaccharidases. In: Scriver CR, Beaudet
AL, Sly WS, et al., eds. The Metabolic and Molecular Bases of Inherited
Disease, 7th ed. New York: McGraw-Hill, 1995.
Luduena RF. Learning Biochemistry: 100 Case-Oriented Problems. New York:
Wiley-Liss, 1995.
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