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CASE FILES: BIOCHEMISTRY
Figure 20-2. The mobilization of glycogen in the liver in response to hor-
monal signals. Binding of the hormones glucagon and/or epinephrine causes
the activation of adenylate cyclase resulting in the production of cyclic AMP,
which activates protein kinase A. By phosphorylation reactions, protein kinase
A inactivates glycogen synthase, activates a cascade that results in active
glycogen phosphorylase, and produces an active inhibitor of protein phos-
phatase 1.
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